Success! The link has been copied to your clipboard.

Profile A
An "A" profile indicates that the patient's plasma refill rate is occurring at the same or a greater rate than ultrafiltration. This profile suggests that the ultrafiltration rate might be increased without immediate risk of intradialytic symptoms.

Profile B
A "B" profile is a gradual slope that has been targeted to find the best compromise between a high ultrafiltration rate and the prevention of intradialytic symptoms. The ideal slope is not a fixed percentage of change in BV, and will vary from patient to patient.

Profile C
A "C" profile is represented by a steep slope which indicates a rapid decrease in blood volume, and bears a higher risk for intradialytic symptoms such as lightheadedness, nausea, vomiting, cramping or hypotension.
Fluid Management Findings
Key Findings from Publications:
- Therapy guided by Relative Plasma Volume (RPV) slope may serve as a valid tool to better achieve target weight using augmented reduction therapy among hemodialysis patients.2
- RPV monitoring yields information that is prognostically important and independent of several risk factors including UF volume, aggressiveness of UF and interdialytic ambulatory blood pressure.3
- RPV monitoring can assist in better achieving target weight.4
- RPV has been used to find the best compromise between a high ultrafiltration rate and the prevention of intradialytic symptoms.2,5,6,7,8,9
- Agarwal, R, Alborzi, P, Satayan, S. Light RP “Dry-weight Reduction in Hypertensive Hemodialysis Patients (DRIP): A Randomized , Controlled Trial.” Hypertension 53 no. 3 (2009) 500-507.
- Sinha AD, Light RP, Agarwal R: “Relative Plasma Volume Monitoring During Hemodialysis Aids the Assessment of Dry Weight.” Hypertension 55 (2010): 305-3110.
- Agarwal, R. “Hypervolemia is Associated With Increased Mortality Among Hemodialysis Patients.” Hypertension 56 (2010): 512-517.
- Agarwal, R, Alborzi, P, Satayan, S. Light RP “Dry-weight Reduction in Hypertensive Hemodialysis Patients (DRIP): A Randomized , Controlled Trial.” Hypertension 53 (2009): 500-507.
- Rodriguez HJ, Domenici R, Diroll A, Goykhman I. “Assessment of Dry Weight by Monitoring Changes in Blood Volume During Hemodialysis using Crit-Line.” Kidney Int 68 (2005): 854-861.
- Goldstein S, Smith C, Currier H. “Non-invasive Interventions to Decrease Hospitalization and Associated Costs for Pediatric Patients Receiving Hemodialysis.” JASN 14 (2003), 2127-2131.
- Michael M, Brewer ED, Goldstein SL. “Blood Volume Monitoring to Achieve Target Weight in Pediatric Hemodialysis Patients” Pediatri Nephrol 19 no. 4 (2004) 432-437.
- Reddan, DN, Szczech LA et al. “Intradialytic Blood Volume Monitoring in Ambulatory Hemodialysis Patients: A Randomized Trial” J Am Soc Nephrol 16 (2005): 2162-2169.
- Jain SR, Smith L, Brewer ED, Goldstein SL. “Non-invasive Intravascular Monitoring in the Pediatric Hemodialysis Population” Pediatri Nephrol < 18 no. 1 (2001) 15-8.

Radioisotope blood volume measurement
LEARN MORE

Reducing Symptoms During Hemodialysis by Continuously Monitoring the Hematocrit
LEARN MORE

Hematocrit as an Indicator of Blood Volume and a Predictor of lntradialytic Morbid Events
LEARN MORE
Caution: Federal (US) law restricts these devices to sale by or on the order of a physician.
Note: Read the Instructions for Use for safe and proper use of these devices. For a complete description of hazards, contraindications, side effects and precautions, see full package labeling.
© 2017-2020, Fresenius Medical Care. All Rights Reserved. Fresenius Medical Care, the triangle logo, 2008T BlueStar, Crit-Line and CLiC are trademarks of Fresenius Medical Care Holdings, Inc. or its affiliated companies. All other trademarks are the property of their respective owners. P/N 102249-01 Rev G 03/2020