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Speedswap®: Keep the Cartridge, Swap the Filter

Clotting or clogging of the circuit is a common occurrence associated with kidney replacement therapy.1 As a result, this may cause therapy downtime and can lead to clinician frustration, increased cartridge utilization, and increased blood loss.1,2

The Speedswap® cartridge allows you to change a flow-compromised NxStage® filter without replacing the cartridge using a pre-attached—yet detachable—filter.3

Join us for a webinar with Dr. Christopher Hebert and Dr. Matthew Trainor as they highlight how this novel technology may:

  • Benefit your ICU patients4
  • Reduce the nursing workload4
  • Decrease therapy costs5

About the Presenters:

Melinda Keto, Senior Healthcare Consultant, Healthcare Design Specialists LLC

Christopher Hebert, MD*
Dr. Christopher Hebert specializes in ICU Nephrology, is an attending physician at Baylor University Medical Center, treating patients with acute kidney injury (AKI), and is founder of Kidney and Hypertension Associates of Dallas. He is a recognized authority on thrombotic microangiopathy, acute kidney injury in the setting of extracorporeal membrane oxygenation, hypertension, and hyponatremia.


Melinda Keto, Senior Healthcare Consultant, Healthcare Design Specialists LLC

Matthew Trainor, MD
Dr. Matthew Trainor currently serves as the Chief of Nephrology at UMass Memorial Marlborough Hospital in Marlborough, MA, and the Medical Director of University Dialysis Services at UMass Memorial Medical Center in Worcester, MA. He also serves as the Medical Director of Worcester County Dialysis in Worcester, MA. Dr. Trainor attended medical school at the College of Dublin Medical School in Dublin, Ireland, and went on to complete his Fellowship in Nephrology at the University of Massachusetts Medical School in Worcester MA, where he is currently an Assistant Professor in the Department of Medicine—Nephrology. 

*Paid speaker for NxStage Medical, Inc.
Paid consultant for NxStage Medical, Inc.


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The NxStage System One is indicated for the treatment of acute and chronic renal failure or fluid overload using hemofiltration, hemodialysis, and/or ultrafiltration, in an acute care facility. The NxStage Cartridge Express with Speedswap is an optional accessory device to be used exclusively with the NxStage System One for facilitating the removal and replacement of a flow-compromised filter during treatment of acute and chronic renal failure or fluid overload. The device would be used when hemofiltration, hemodialysis, and/or ultrafiltration may become disrupted.4 All treatments must be administered under a physician’s prescription and must be observed by a trained and qualified person, considered to be competent in the use of this device by the prescribing physician. Kidney replacement therapy, as with any medical therapy, is not without risks. The decision of which therapy to use should be made by the physician, based on previous experience and on the individual facts and circumstances of the patient. There is no literature demonstrating one therapy is clinically better than another.6 NxViewTM is contraindicated as the sole method of monitoring a patient during treatment.4

The Speedswap cartridge can only be used with the following software versions and user guide:

  • NxView Software 3.0 or higher
  • System One™ Cycler Software 4.14 or higher
  • NxStage System One User Guide NC4921 Rev. J or higher

1. Joannidis M, Oudemans-van Straaten HM. Clinical Review: Patency of the Circuit in Continuous Renal Replacement Therapy. Crit Care 2007;11(4):218.
2. Cortina G, McRae R, Chiletti R, Butt W. The effect of patient- and treatment-related factors on circuit lifespan during continuous renal replacement therapy in critically ill children. Pediatr Crit Care Med. 2020;21:578-585.
3. NxStage Cartridge Express with Speedswap, CAR-535 and NxStage Speedswap Express Kit, SSK-535 IFU. NC45-0926 Rev. F 2022.
4. NxStage System One Critical Care User Guide. NC4921 Rev. M 2022.
5. Data on File, 01/2022.
6. Nash et al. Journal of Critical Care. Volume 41, October 2017, pages 138-144.