Stay Safe continuous ambulatory peritoneal dialysis

  stay·safe® CAPD System

Continuous ambulatory peritoneal dialysis (CAPD) is a simple, safe, and effective peritoneal dialysis (PD) technique, especially for patients who have been identified as low or low-average transporters.1

Learn More About stay•safe CAPD

To learn more about stay•safe, please fill out the form below.

Consider CAPD for Incident and Incremental End Stage Renal Disease (ESRD) Patients

  • 85 percent of incident end stage renal disease (ESRD) patients start dialysis with a GFR >5mL/min/1.73m22
  • The CAPD modality can provide a gentler onboarding process

Potential Benefits of CAPD for ESRD Patients 

  • Better preservation of residual kidney function3
  • Greater ultrafiltration and sodium removal for appropriate patients4
  • Increased phosphorus clearance5
  • Improved sleep quality6

stay•safe - An Innovative Design to Support CAPD Patients

stay•safe’s simple and smart product design supports patients during a CAPD exchange and is designed to reduce patient dropouts due to technique failure, infections, burnout, or other common reasons. The goal is to make the therapy more intuitive and help patients in reducing procedural steps to reduce the overall therapy burden in the long run.

A. Every PD exchange starts with “Drain” by default.

B. The stay•safe DISC with the blue dial guides the patients in only 4 steps: Drain, Flush, Fill, and Close. The stay•safe DISC eliminates the need to clamp and unclamp lines. It may be easier to train patients on stay·safe CAPD.7

C. The stay•safe PIN automatically closes the catheter extension set before disconnection.

Three Unique stay•safe CAPD Features

The stay•safe CAPD system’s is designed to help patients perform their daily self-care CAPD treatment in a safe and convenient way. The stay•safe CAPD system’s unique features including the stay•safe DISC, stay•safe PIN, and stay•safe Organizer work together to promote ease of use.

The stay•safe Organizer

The stay•safe Organizer is designed to bring all parts of the stay•safe CAPD system together and includes built-in locations for the stay•safe catheter extension set and stay•safe cap. This all-in-one Organizer simplifies the patient’s role in the CAPD exchange procedure.

The stay•safe DISC

The central part of the stay•safe CAPD system is the DISC with its distinctive blue dial. By simply turning the dial, the patient performs all the essential steps of the CAPD procedure: drain, flush, fill, and close.

The stay•safe PIN Technology

When turning the dial to the fourth step (PIN/Close), a PIN is inserted into the catheter extension set before disconnecting from the system. The number of systems openings is reduced by 50% which may reduce the potential risk of contamination.

stay•safe CAPD Design — Easy to Learn, Easy to Use

Intuitive operation and simple patient instructions designed to promote successful treatment

Step 1: Drain

 To begin, open the clamp on the catheter extension set. The dial is already set to Position 1 (Drain).

Step 3: Fill

After the Flush step, turn the dial to Position 3 to Fill the peritoneal cavity with DELFLEX® Dextrose Peritoneal Dialysis Solution. The stay•safe DISC allows control of fluid flow during the Fill.

Step 2: Flush

Once the Drain step is completed, turn the dial to Position 2 to Flush the tubing.

Step 4: PIN/Close

When the Fill step is completed, turn the dial to the final Position 4 to PIN/Close.

stay•safe PIN Technology

Catheter connection technique is known to be a factor contributing to peritonitis rates.8 With the stay•safe system’s patented PIN technology, the potential for accidental contamination and subsequent infection may be reduced.

The stay•safe PIN seals the fluid pathway prior to catheter extension set disconnection during both CAPD and APD. With only one system opening per treatment, the stay•safe CAPD system has half the openings of conventional CAPD systems, which may reduce the potential risk of touch contamination


25 Years of stay•safe

Since 1996, stay•safe has provided trusted CAPD technology to peritoneal dialysis patients around the world technology to dialysis patients around the world and has been in the U.S. market since 2004.

The stay•safe PIN technology is used in APD with the Liberty®Select cycler. Today, over 20,000 PD patients in the U.S. benefit from the advantages of the stay•safe PIN technology to perform CAPD and APD with ease.





  1. Blake PG & Daugirdas JT, Physiology of Peritoneal Dialysis, Handbook of Dialysis 5th edition, pp. 392 -407.
  2. United States Renal Data System. 2020 USRDS Annual Data Report: Epidemiology of kidney disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2020.
  3. Nongnuch, A., Assanatham, M., Panorchan, K., Davenport, A., Strategies for preserving residual renal function in peritoneal dialysis patients, Clinical Kidney Journal, Volume 8, Issue 2, April 2015, Pages 202–211,
  4. Maharjan SRS, Davenport A. Comparison of sodium removal in peritoneal dialysis patients treated by continuous ambulatory and automated peritoneal dialysis. J Nephrol. 2019 Dec;32(6):1011-1019.
  5. Courivard & Davenport (2015) Phosphate removal in PD; Peritoneal Dialysis International, Vol. 36, pp.85–93.
  6. Roumeliotis et al (2020), APD or CAPD: one glove does not fit all. Int. Urology and Nephrology,
  7. Lambert, MC, Lage, C, Kirchgessner, J., stay•safe®. A new PVC free system. EDTNA|ERCA JOURNAL 1999 XXV 3.
  8. Port, F.K., P.J. Held, K.D. Knolph, M.N. Turenne, R.A. Wolfe. “Risk of Peritonitis and Technique Failure by CAPD Connection Technique: A National Study.” Kidney International 42 (1992): 967-974.

Indications for Use: DELFLEX is indicated in the treatment of chronic kidney failure in patients being maintained on peritoneal dialysis.

DELFLEX is available by prescription only.


  • Intended for intraperitoneal administration only
  • Not for intravenous or intra-arterial administration
  • Use aseptic technique throughout the procedure
  • Monitor routinely for electrolyte, fluid, and nutrition imbalances
  • Monitor for signs of peritonitis or overfill
  • Inspect the drained fluid for fibrin or cloudiness
  • Ensure that there is no leakage around the catheter
  • Solution-related adverse reactions may include peritonitis, catheter site infection, electrolyte and fluid imbalances, hypovolemia, hypervolemia, hypertension, disequilibrium syndrome, muscle cramping, abdominal pain, abdominal distension, and abdominal discomfort

To report SUSPECTED ADVERSE REACTIONS, contact Fresenius Medical Care North America at 800-323-5188. You are encouraged to report negative side effects of prescription drugs to the FDA at 1-800-FDA-1088 or Visit MedWatch or call 1-800-FDA-1088.

Fresenius CAPD stay•safe® Disposable Administration Sets with stay•safe® Connector:

The Fresenius CAPD stay•safe® Disposable Administration Sets with stay•safe® Connector is indicated for use in end-stage acute and chronic renal disease.
Liberty® Select

stay•safe Catheter extension set:

The stay•safe catheter extension set with Luer-Lock is indicated for use in patients with acute and chronic end-stage renal disease undergoing peritoneal dialysis (PD) in a healthcare facility or at home. The stay•safe catheter extension set with Luer-Lock is used to connect a PD catheter with a Luer-Lock catheter adapter to PD systems that use stay•safe PIN technology.

stay•safe Cap:

The Fresenius sterile stay•safe® Cap is intended to be used for closure of the stay safe stay•safe peritoneal dialysis connectology system.

Liberty Select Cycler:

Indications for Use: The Fresenius Liberty Select Cycler is indicated for acute and chronic peritoneal dialysis.

Caution: Federal (US) law restricts this device to sale by or on the order of a physician.

Note: Read the Instructions for Use for safe and proper use of this device. For a complete description of hazards, contraindications, side effects, and precautions, see full package labeling at

©2009, 2018-2023 Fresenius Medical Care. All Rights Reserved. Fresenius Medical Care, the triangle logo, Liberty, stay·safe, and DELFLEX are trademarks of Fresenius Medical Care Holdings Inc. or its affiliated companies. All other trademarks are the property of their respective owners. P/N 100969-01 Rev F 06/2023