NxStage System One is a simple, flexible and portable system providing patients options for hemodialysis treatments.
NxStage System One was designed with patients in mind to provide simplicity, flexibility and portability without compromising safety. System One was designed to overcome the challenges posed by traditional equipment and is the first truly portable hemodialysis system for home and clinic use.
Improving Quality of Life
More frequent home hemodialysis (HHD), during the day or overnight (NHHD), may provide significant clinical and quality of life benefits including:
More energy1-3
Improved appetite4
Quicker time to recovery5
Lower risk of death6
Making Dialysis Accessible
The simple interface is designed to be easy to learn and use
Simple plumbing connections and standard electrical plug minimize the impact in patients’ homes
Easy-to-use drop-in cartridge allows for easy wipe-down disinfection after each use
Our 24/7 dedicated technical support team offers your patients peace of mind while dialyzing, no matter when or where
Portability gives your patients freedom to dialyze within the comfort of their own home, and may offer the ability to travel
Ease of use extends to the steps to begin a treatment: Insert a single-use cartridge into the cycler, spike a bag of saline, and press the start priming button on the touch screen. Pressing the ‘Guide Me’ button displays step-by-step illustrated instructions to assist in a particular task.
A state of the art telehealth platform for the collection and delivery of home hemodialysis treatment and patient medical information.
Risks and Responsibilities
Patients should review the following information carefully and discuss it with their doctors to decide whether home hemodialysis with NxStage systems is right for them.
Users should weigh the risks and benefits of performing home hemodialysis with NxStage systems.
Medical staff will not be present to respond to health emergencies that might happen during home treatments, including, among other things, dizziness, nausea, low blood pressure, and fluid or blood leaks.
Users may not experience the reported benefits of home, more frequent, or nocturnal hemodialysis with the NxStage systems.
The NxStage systems require a prescription for use.
Users will be responsible for all aspects of their hemodialysis treatment from start to finish.
Medical staff will not be present to perform home treatments. Users will be responsible for, among other things, equipment setup, needle insertions, responding to and resolving system alarms, system tear-down after treatment, monitoring blood pressure, ensuring proper aseptic technique is followed, and following all the training material and instructions that nurses provide.
Users will need additional resources to perform home hemodialysis.
Users will need a trained care partner to be present during your treatment at home (unless their doctor prescribes “solo/independent” home hemodialysis, described below).
Users must have a clean and safe environment for their home treatments.
Users will need space in their home for boxes of supplies necessary to perform home hemodialysis with NxStage systems.
Certain forms of home hemodialysis have additional risks.
If a doctor prescribes home hemodialysis more than 3 times a week, vascular access is exposed to more frequent use which may lead to access related complications, including infection of the site. Doctors should evaluate the medical necessity of more frequent treatments and discuss the risks and benefits of more frequent therapy with users.
If a doctor prescribes “solo/independent” home hemodialysis without a care partner during waking hours, risks of significant injury or death increase because no one is present to help users respond to health emergencies. If users experience needles coming out, blood loss, or very low blood pressure during solo/independent home hemodialysis, they may lose consciousness or become physically unable to correct the health emergency. Users will need additional ancillary devices and training to perform solo/independent home hemodialysis.
If a doctor prescribes “nocturnal” home hemodialysis at night while the user and a care partner are sleeping, risks increase due to the length of treatment time and because therapy is performed while the user and a care partner are sleeping. These risks include, among other things, blood access disconnects and blood loss during sleep, blood clotting due to slower blood flow or increased treatment time or both, and delayed response to alarms when waking from sleep. A doctor may need to adjust users’ medications for nocturnal home hemodialysis, including, among other things, iron, Erythropoiesis-Stimulating Agents (ESA), insulin/oral hypoglycemics, anticoagulants, and phosphate binders.
References:
Finkelstein FO, Schiller B, Daoui R, Gehr TW, Kraus MA, Lea J, Lee Y, Miller BW, Sinsakul M, Jaber BL. At-home short daily hemodialysis improves the long-term health-related quality of life. Kidney Int. 2012 Sep;82(5):561-9.
Ting GO, Kjellstrand C, Freitas T, Carrie BJ, Zarghamee S. Long-term study of high-comorbidity ESRD patients converted from conventional to short daily hemodialysis. Am J Kidney Dis. 2003;42(5):1020-1035.
Goldfarb-Rumyantzev AS, Leypoldt JK, Nelson N, Kutner NG, Cheung AK. A crossover study of short daily haemodialysis. Nephrol Dial Transplant. 2006;21:166-175.
Spanner E, Suri R, Heidenheim AP, Lindsay RM. The impact of quotidian hemodialysis on nutrition. Am J Kidney Dis. 2003;42(1 suppl):30-35.
Jaber BL, Lee Y, Collins AJ, et al. Effect of daily hemodialysis on depressive symptoms and postdialysis recovery time: interim report from the FREEDOM (Following Rehabilitation, Economics and Everyday-Dialysis Outcome Measurements) Study. Am J Kidney Dis. 2010;56(3):531-539.
Weinhandl ED, Lie J, Gilbertson DT, Arneson TJ, Collins AJ. Survival in daily home hemodialysis and matched thrice-weekly in-center hemodialysis patients. J Am Soc Nephrol. 2012;23(5):895-904.
